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Myocardial infarction (MI) is the death (necrosis) of a large or small area of heart muscle (myocardium). The cardiac muscle cells in this area are no longer able to contract due to a lack of oxygen supply and die within a few hours.

The myocardium is vascularized by the coronary arteries. When these become blocked (clot, thrombosis or spasm), the myocardium no longer receives blood and lacks oxygen. It suffers from ischemia.

The severity of the infarction depends mainly on its extent: the larger the area of the blocked artery, the more serious the infarction. If the damage is very extensive, the functioning of the entire heart pump is altered.

Myocardial infarction (MI) is one of the major complications of atherosclerosis of the coronary arteries. It affects one man in five between the ages of 40 and 60, but also affects women and younger people to a significant degree.